Napoli vs. Real Madrid odds, picks and predictions

Nathan Beighle
Staff Writer

Napoli (1 win, 0 draws, 0 losses) welcomes Real Madrid (1-0-0) to Stadio Diego Armando Maradona Tuesday. Kickoff in Naples, Italy is set for 3 p.m. ET. Below, we analyze FanDuel Sportsbook's lines around the Napoli vs. Real Madrid odds, and make our best Champions League bets, picks and predictions.

Napoli beat Braga 2-1 on the road Sept. 20 to open up its Champions League group stage play. It ended with 2 more shots and 4 more shots on target than its opponent. Napoli made the league last season but lost 2-1 in aggregate to AC Milan in the quarterfinals. It is 4-2-1 in Serie A play this season and is led by F Victor Osimhen, who has 5 goals in 7 matches.

Real Madrid beat Union Berlin 1-0 at home on Sept. 20. It ended with 32 shots and 7 on frame which compared favorably to Union's 4 and 0. Real lost 5-1 in aggregate in the semifinal of the Champions League last season to Manchester City. It is 7-0-1 in La Liga play and is led by M Jude Bellingham, who has 6 goals in 7 matches.

Napoli vs. Real Madrid odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:19 a.m. ET.

  • Moneyline: Napoli +165 (bet $100 to win $165) | Real Madrid +155 (bet $100 to win $155) | Draw +250 (bet $100 to win $250)
  • Over/Under: 2.5 (O: -146 | U: +120)

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Napoli vs. Real Madrid picks and predictions


Real Madrid 2, Napoli 1

Moneyline (ML)


Real Madrid lit up Union Berlin to open its group stage. Union finished 4th in the Bundesliga last season. While Napoli is a competent side in Serie A, Madrid, like Man City, is a level above most and should be able to go on the road and come out on top.

Real is 4-0-1 on the road this season and was 11-1-7 on the road last season in league play. Real was 1-1-1 on the road in the group stage last season but had 0.5 or more expected goals than their opponent in 2 of those 3 games.

Napoli, while it won, didn't have a great showing against Braga. It also lost on the road against its best group stage opponent last season, Liverpool, a 2-0 defeat in which it had 0.4 expected goals and Liverpool had 2.4.

Expect it to struggle in this one and take REAL MADRID (+155).

Over/Under (O/U)

LEAN OVER 2.5 (-146).

Napoli went Over this total in 5 of 6 group stage matches last season. Real topped this total in 4 of 6 group stage matches.

Both teams have dynamic scorers and have proven that in their respective leagues. Napoli is averaging 2.29 goals per game with Real at 2.0 per game.  Take OVER 2.5 (-146).

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